FRONTLINE SPRAY, FRONTLINE PLUS, (FIPRONIL) from Merial

Fipronil is a broad-spectrum insecticide available as a spray or drip-on. Fipronil binds chemically to the hair and is absorbed through the hair follicle by the sebaceous glands. In spray formulation fipronil kills fleas at 95% for over 80 days after application on dogs and for 1 month with biweekly bathing. It is labeled for puppies and kittens of 8 weeks and the product is not washed off by bathing. It is also affective against ticks. The major problem with the spray is the high volume of alcohol-based product that must be applied. Many cats will show minor adverse reactions with this application technique. The product must be applied no more than once a month. Frontline Plus contains the insect growth regulator, S-methoprene and so provides control of eggs and adult fleas.